COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIAC AND VASCULAR DISEASE

摘要

The invention provides methods for the treatment of coronary heart disease, peripheral vascular disease, stroke, and ischemia featuring agents that interfere with the expression or activity of Cthrcl. The invention also provides the use of Cthrcl peptide as a therapeutic agent for the treatment of acute or chronic cardiac deficiencies. The invention further provides detection and monitoring of Cthrcl peptide in blood or serum to assess or monitor cardiac function.