发明名称 NOVEL SOLID STATE FORMS OF RANOLAZINE SALTS
摘要 Provided herein are solid state forms of ranolazine salts. Also provided is a stable amorphous form of ranolazine hydrochloride having a water content of less than about 0.5% by weight. Further provided are amorphous co-precipitates of ranolazine or a pharmaceutically acceptable salt thereof with povidone. Processes for the preparation of ranolazine forms, pharmaceutical compositions, and methods of treating thereof are also included. The solid state forms of ranolazine salts are useful for preparing ranolazine in high purity.
申请公布号 US2011300218(A1) 申请公布日期 2011.12.08
申请号 US200913063029 申请日期 2009.09.08
申请人 ATHUKURI VENKATA SUBBARAO;SWAMY SAIDUGARI;KHUNT MAYUR DEVJIBHAI;PRADHAN NITIN SHARADEHANDRA;ACTAVIS GROUP PTC EHF 发明人 ATHUKURI VENKATA SUBBARAO;SWAMY SAIDUGARI;KHUNT MAYUR DEVJIBHAI;PRADHAN NITIN SHARADEHANDRA
分类号 A61K9/14;A61K31/495;A61P9/10;C07D295/145 主分类号 A61K9/14
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