| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a recently discovered macrophage specific receptor, CRIg, and the use thereof in the prevention and treatment of complement-associated disorders, including complement-associated eye conditions, such as age-related macular degeneration (AMD) and choroidal neovascularization (CNV). <P>SOLUTION: A method for the prevention or treatment of a complement-associated eye condition comprises administering to the subject in need a prophylactically or therapeutically effective amount of a complement inhibitor, such as an inhibitor of the alternative complement pathway, e.g., a CRIg polypeptide or an agonist thereof. <P>COPYRIGHT: (C)2012,JPO&INPIT |
