发明名称 PROTECTIVE ANTI-GLUCAN ANTIBODY WITH PREFERENCE FOR β-1,3-GLUCAN
摘要 <P>PROBLEM TO BE SOLVED: To provide good and further better monoclonal antibodies for inducing therapeutic immune responses against infections, particularly against microbial infections. <P>SOLUTION: There are provided monoclonal antibodies that bind to &beta;-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly treatment against Candida albicans and Aspergillus fumigatis infections. The antibodies are not specific for &beta;-1,6-glucan. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2011244828(A) 申请公布日期 2011.12.08
申请号 JP20110168831 申请日期 2011.08.01
申请人 CASSONE ANTONIO 发明人 CASSONE ANTONIO;TOROSANTUCCI ANTONELLA
分类号 C12N15/09;A61K39/395;A61K48/00;A61P31/04;A61P31/10;C07K16/12;C07K16/14;C07K16/28;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08 主分类号 C12N15/09
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