METHODS AND COMPOSITIONS FOR ORAL PHARMACEUTICAL THERAPY
摘要
It now has been found that oral administration of pharmaceutical agents, including N-methylol transfer agents such as Taurolidine may be used to provide efficacious blood plasma concentration of the agents for treatment of diseases by providing release of the active agent into the duodenum or jejunum of a patient and/or at a pH of about 5.4 to about 6.5. Embodiments of the invention therefore provide oral dosage forms, compositions and methods for administration of pharmaceutical agents to the duodenum or jejunum of a patient, and/or which release at a pH of about 5.4 to about 6.5.
申请公布号
WO2011151722(A2)
申请公布日期
2011.12.08
申请号
WO2011IB01539
申请日期
2011.06.01
申请人
GEISTLICH PHARMA AG;PFIRRMANN, ROLF, W.;GEISTLICH, PETER