| 摘要 |
A tumor discriminator determines if a biological sample is diseaseous. Summarized expression value samples in a reference dataset are determined. The summarized expression value being a summation of gene expression levels for disease and normal samples. A biological sample summarized expression value is determined using a gene expression profile for a biological sample. A disease sample distance is estimated from the biological sample summarized expression value to a location in the disease sample space. The disease sample space defined by a statistical analysis of the disease samples. A normal sample distance is estimate from the biological sample summarized expression value to a location in the normal sample space The normal sample space defined by a statistical analysis of the normal samples. The disease sample distance is compared with the normal sample distance to determine if the biological sample is diseaseous. |
