发明名称 |
PREDICTING PLAQUE COMPOSITION AND PHENOTYPE IN CORONARY ARTERIES VIA HDL-SUBCLASS ANALYSIS, AND METHODS RELATED THERETO |
摘要 |
The invention provides a method of identifying a subject at increased risk of cardiovascular disease (CVD) and/or soft plaque that provides an HDL subpopulation by separating the ApoA-I-containing HDL particles from a plasma sample from the subject, where the HDL particles include an alpha 1-4 (a1-4) subpopulation, a pre-alpha 1-4 (pre-a1-4) subpopulation, and a pre-beta 1-2 (?re-ß1-2) subpopulation, creating an HDL subpopulation profile by quantitating the HDL subpopulations, correlating the HDL subpopulation profile with reference HDL subpopulation profile values; and determining whether the subject has an increased risk, a borderline risk, or a low risk for CVD. |
申请公布号 |
WO2011153271(A1) |
申请公布日期 |
2011.12.08 |
申请号 |
WO2011US38801 |
申请日期 |
2011.06.01 |
申请人 |
BOSTON HEART LAB;SCHAEFER, ERNST, J.;ASZTALOS, BELA, F. |
发明人 |
SCHAEFER, ERNST, J.;ASZTALOS, BELA, F. |
分类号 |
G01N33/566 |
主分类号 |
G01N33/566 |
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