A GENE EXPRESSION PROFILE OF BRCA-NESS THAT CORRELATES WITH RESPONSIVENESS TO CHEMOTHERAPY AND WITH OUTCOME IN CANCER PATIENTS

摘要

Aspects of the invention provide methods and compositions for evaluating cells and tissues based on gene expression profiles to determine their sensitivity or resistance to one or more chemotherapeutic agents. A patient having a tumor or cancer can be evaluated using a gene expression profile to assist in determining the disease prognosis, selecting an appropriate therapy, and/or predicting drug resistance or sensitivity.