发明名称 |
ANTIBODY AND USE THEREOF |
摘要 |
<p>Disclosed is a cell proliferation inhibitor which contains, as an antibody component, an artificially produced anti-EGFR antibody that specifically binds to an EGFR, said anti-EGFR antibody being characterized in that the epitope is present in the cysteine-rich subdomain 2 (C2 domain) among the four subdomains constituting an extracellular domain of the EGFR and/or the epitope is present in the ligand-binding domain 1 (L1 domain) among the four subdomains constituting an extracellular domain of the EGFR.</p> |
申请公布号 |
WO2011152525(A1) |
申请公布日期 |
2011.12.08 |
申请号 |
WO2011JP62810 |
申请日期 |
2011.06.03 |
申请人 |
TOAGOSEI CO.,LTD.;KEIO UNIVERSITY;SHIMIZU NOBUYOSHI;TAKAYANAGI ATSUSHI;YOSHIDA TETSUHIKO |
发明人 |
SHIMIZU NOBUYOSHI;TAKAYANAGI ATSUSHI;YOSHIDA TETSUHIKO |
分类号 |
C12N15/09;A61K39/395;A61P35/00;C07K16/28 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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