| 发明名称 |
AMINOPYRIMIDINE DERIVATIVES AS LRRK2 INHIBITORS |
| 摘要 |
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n. X, R1, R2, R3, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease. |
| 申请公布号 |
US2011301141(A1) |
申请公布日期 |
2011.12.08 |
| 申请号 |
US201113150929 |
申请日期 |
2011.06.01 |
| 申请人 |
BAKER-GLENN CHARLES;BURDICK DANIEL JON;CHAMBERS MARK;CHAN BRYAN K.;CHEN HUIFEN;ESTRADA ANTHONY;GUNZNER-TOSTE JANET;SHORE DANIEL;SWEENEY ZACHARY;WANG SHUMEI;ZHAO GUILING;GENENTECH, INC. |
发明人 |
BAKER-GLENN CHARLES;BURDICK DANIEL JON;CHAMBERS MARK;CHAN BRYAN K.;CHEN HUIFEN;ESTRADA ANTHONY;GUNZNER-TOSTE JANET;SHORE DANIEL;SWEENEY ZACHARY;WANG SHUMEI;ZHAO GUILING |
| 分类号 |
A61K31/5377;A61K31/506;A61K31/5386;A61K31/553;A61P25/16;C07D401/12;C07D401/14;C07D403/12;C07D413/12 |
主分类号 |
A61K31/5377 |
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