| 发明名称 |
Chemically modified oligonucleotides |
| 摘要 |
<p>This invention relates to compositions and methods for making and using chemically modified oligonucleotides 5 agents for inhibiting gene expression. 2949604_1 (GHMatters) P73650.AU. 1 111ii 1 O==P---O 0 JigandItethering attachment point carie / U,- GAND RM backbone attachment points carrier - tether O==P--' Ri R w R -R4 FG' R = H, protecting group; A: Rar=r ) + (LIGAND) B:cCrO 0(</p> |
| 申请公布号 |
AU2011250733(A1) |
申请公布日期 |
2011.12.08 |
| 申请号 |
AU20110250733 |
申请日期 |
2011.11.11 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
MANOHARAN, MUTHIAH;KESAVAN, VENKITASAMY;RAJEEV, KALLANTHOTTATHIL G. |
| 分类号 |
C07H21/04;A61K31/70 |
主分类号 |
C07H21/04 |
| 代理机构 |
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| 主权项 |
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