发明名称 |
Structural carotenoid analogs for the inhibition and amelioration of disease |
摘要 |
<p>A chemical compound having the structure
where each Y is independently O or H 2 ;
where each R is independently -alkyl-NR 2 3 , -alkyl-CO 2 - , or -amino acid-NH 3 + ;
where each R 2 is independently H, alkyl, or aryl, as well as its use in treating cardiovascular disease, a disease which produces reactive oxygen species, liver disease, disease which comprises cancerous and pre-cancerous cell(s), disease comprising increasing cannexin 43 expression or reducing C-reactive protein, gastrointestinal disease, muscoskeletal disease.</p> |
申请公布号 |
EP2392562(A1) |
申请公布日期 |
2011.12.07 |
申请号 |
EP20100185924 |
申请日期 |
2003.07.29 |
申请人 |
CARDAX PHARMACEUTICALS, INC. |
发明人 |
LOCKWOOD, SAMUEL, FOURNIER;O'MALLEY, SEAN;WATUMULL, DAVID, G.;HIX, LAURA, M.;JACKSON, HENRY;NADOLSKI, GEOFF |
分类号 |
C07C403/24;A01N27/00;A61K31/01;A61K31/015;A61K31/045;A61K31/07;A61K31/075;A61K31/12;A61K31/13;A61K31/185;A61K31/215;A61K31/225;A61K31/255;A61K31/325;A61K31/401;A61K31/404;A61K31/4172;A61K31/535;A61K31/537;A61K31/5377;A61K31/66;A61K31/6615;A61K31/665;A61K31/70;A61K31/7024;A61K31/704;A61K31/715;A61P1/16;A61P9/04;A61P9/06;A61P35/00;C07D207/16;C07D233/60;C07D265/30;C07D307/58;C07F9/02;C07F9/117;C07H13/04 |
主分类号 |
C07C403/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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