| 摘要 |
PURPOSE: A compound from gloiopeltis furcata is provided to use as a treatment of Alzheimer's disease due to the anticholinesterase-activity by moderate activity about acetylcholinesterase and butylcholinesterase. CONSTITUTION: A compound from gloiopeltis furcata, which is (5E, 7E)-9-oxodeca-5,7-dienoic acid or a pharmaceutical thereof, is in the chemical formula 11. A composition for preventing and curing of Alzheimer's disease comprises one or more compounds selected from 2-(3-hydroxy-5-oxotetrahydrofuran-3-yl) acetic acid, glutaric acid, succinic acid, nicotinic acid, (E)-4-hydroxyhex-2-enoicacid, cholesterol, 7-hydroxycholesterol, uridine, glycerol, 5-(hydroxymethyl)-2-methoxybenzene-1,3-diol, (5E,7E)-9-oxodeca-5,7-dienoic acid, (Z)-3-ethylidene-4-methylpyrrolidine-2,5-dione, dehydrovomifoliol, loliolide, cholesterylstearate, palmitic acid, cis-5,8,11,14,17-eicosapentaenoic acid, and α-linolenic acid. |
