| 发明名称 |
FINELY PULVERIZED PHARMACEUTICAL COMPOSITION |
| 摘要 |
<p>An objective of the present invention is to provide a composition that has improved oral absorption and comprises a slightly soluble drug, and to provide a process for producing the same. According to the present invention, there is provided a finely pulverized composition comprising a slightly soluble drug such as 22²-methoxyolean-12-ene-3², 24(4²)-diol and a hydrophilic surfactant. According to the present invention, there is also provided a process for producing the finely pulverized composition according to the present invention, characterized in that , after the dispersion of a slightly soluble drug and a hydrophilic surfactant in a solvent, the dispersion is pulverized with a high-pressure homogenizer.</p> |
| 申请公布号 |
EP2392354(A1) |
申请公布日期 |
2011.12.07 |
| 申请号 |
EP20100735909 |
申请日期 |
2010.01.29 |
| 申请人 |
MEIJI SEIKA PHARMA CO., LTD. |
发明人 |
CHIKASE, SHIGERU;KAWADA, DAI |
| 分类号 |
A61K47/20;A61K9/10;A61K9/14;A61K9/20;A61K31/075;A61K45/00;A61K47/26;A61K47/30;A61K47/32;A61K47/34;A61K47/38;A61P1/16 |
主分类号 |
A61K47/20 |
| 代理机构 |
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代理人 |
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| 主权项 |
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