| 发明名称 |
Anti-C5aR antibodies and uses thereof |
| 摘要 |
The present invention relates to antibodies which bind to C5aR and which are useful in diagnostic and therapeutic methods. The antibodies of the present invention are reactive with an extracellular loop of C5aR other than the N-terminal domain and are capable of substantially reducing or inhibiting the binding of C5a to C5aR and functional consequences of neutrophil chemoattractant receptor activation.
|
| 申请公布号 |
US8071096(B2) |
申请公布日期 |
2011.12.06 |
| 申请号 |
US20050502145 |
申请日期 |
2005.05.05 |
| 申请人 |
MACKAY CHARLES REAY;G2 THERAPIES LTD |
发明人 |
MACKAY CHARLES REAY |
| 分类号 |
A61K39/395;G01N33/48;A61K38/00;A61K39/00;A61K39/104;A61K48/00;A61K49/00;A61K49/04;A61K51/00;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K16/28;C12N5/10;C12N5/20;C12N15/09;C12N15/13;C12P21/08;G01N33/53 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
