| 发明名称 |
RNAi mediated expression inhibition of a cholinergic protein |
| 摘要 |
The present invention relates to nucleic acid sequences producing at least one functional miRNA, at least one functional shRNA and/or at least one functional siRNA, said miRNA, shRNA or siRNA being designed to silence the expression of a gene that encodes a cholinergic protein. The present invention further relates to compositions and kits comprising such nucleic acid sequences as well as to uses thereof. |
| 申请公布号 |
US8071753(B2) |
申请公布日期 |
2011.12.06 |
| 申请号 |
US20090481180 |
申请日期 |
2009.06.09 |
| 申请人 |
BERRARD SYLVIE;LECOMTE MARIE JOSE;MALLET JACQUES;SANTAMARIA JULIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
BERRARD SYLVIE;LECOMTE MARIE JOSE;MALLET JACQUES;SANTAMARIA JULIE |
| 分类号 |
C07H21/04;A61K48/00;C07H21/02;C12N15/63;C12N15/85 |
主分类号 |
C07H21/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
