发明名称 |
Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins |
摘要 |
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens. |
申请公布号 |
US8071107(B2) |
申请公布日期 |
2011.12.06 |
申请号 |
US20040572638 |
申请日期 |
2004.09.17 |
申请人 |
HAYNES BARTON F.;GAO FENG;KORBER BETTE T.;HAHN BEATRICE H.;SHAW GEORGE M.;KOTHE DENISE;LI YING YING;DECKER JULIE;LIAO HUA-XIN;DUKE UNIVERSITY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION |
发明人 |
HAYNES BARTON F.;GAO FENG;KORBER BETTE T.;HAHN BEATRICE H.;SHAW GEORGE M.;KOTHE DENISE;LI YING YING;DECKER JULIE;LIAO HUA-XIN |
分类号 |
A61K39/21;C07H21/04;C12N;C12N5/02;C12N15/74 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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