摘要 |
<P>PROBLEM TO BE SOLVED: To provide a process for improving carbapenem antibiotics using carbapenem intermediates, and to provide a method for retrieving carbapenems in the process. <P>SOLUTION: The method for retrieving products (carbapenems) from a carbapenem crystal mother liquor by an efficient technique, through creating carbapenem intermediates each having structural formula (Ia) to effectively produce Ertapenem, Meropenem and Doripenem, is provided. <P>COPYRIGHT: (C)2012,JPO&INPIT |