METHODS AND COMPOSITIONS USING LISTERIA FOR ADJUVANT TREATMENT OF CANCER
摘要
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
申请公布号
WO2011149852(A1)
申请公布日期
2011.12.01
申请号
WO2011US37602
申请日期
2011.05.23
申请人
ADURO BIOTECH;DUBENSKY, THOMAS, W.;BROCKSTEDT, DIRK, G.;LEONG, MEREDITH;BAHJAT, KEITH, S.
发明人
DUBENSKY, THOMAS, W.;BROCKSTEDT, DIRK, G.;LEONG, MEREDITH;BAHJAT, KEITH, S.