| 发明名称 |
Antibody Glycosylation Variants Having Increased Antibody-Dependent Cellular Cytotoxicity |
| 摘要 |
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to glycosylation engineering to generate proteins with improved therapeutic properties, including antibodies with increased antibody-dependent cellular cytotoxicity. |
| 申请公布号 |
US2011293609(A1) |
申请公布日期 |
2011.12.01 |
| 申请号 |
US201113196724 |
申请日期 |
2011.08.02 |
| 申请人 |
ROCHE GLYCART AG |
发明人 |
UMANA PABLO;JEAN-MAIRET JOEEL;BAILEY JAMES E. |
| 分类号 |
A61K39/395;C12N15/09;A61K38/00;A61P35/00;C07H21/04;C07K16/00;C07K16/18;C07K16/28;C07K16/30;C07K16/42;C07K19/00;C12N5/06;C12N5/10;C12N5/16;C12N5/20;C12N5/24;C12N9/10;C12N15/12;C12N15/13;C12N15/54;C12P21/00;C12P21/06;C12P21/08 |
主分类号 |
A61K39/395 |
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