IMMUNOSUPPRESSANT J2 - SODIUM ALGINATE MICROSPHERE, PREPARATION METHOD AND USE THEREOF

摘要

An immunosuppressant J2 sodium alginate microsphere, its preparation method, and use are disclosed. The microsphere comprises sodium alginate as carrier and immunosuppressant J2. The micosphere is formed by encapsulating or absorbing immunosuppressant J2 into micosphere in presence of calcium ion through a high-voltage electrostatic droplets device. Said microsphere formulation has tissue-targeting, higher bioavailability and lower whole body toxicity.