| 发明名称 |
TREATMENT OF TUMOR SUPPRESSOR GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO THE GENE |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tumor Suppressor genes, in particular, by targeting natural antisense polynucleotides of Tumor Suppressor genes. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Tumor Suppressor genes.
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| 申请公布号 |
US2011294870(A1) |
申请公布日期 |
2011.12.01 |
| 申请号 |
US200913133039 |
申请日期 |
2009.12.03 |
| 申请人 |
COLLARD JOSEPH;SHERMAN OLGA KHORKOVA;OPKO CURNA, LLC |
发明人 |
COLLARD JOSEPH;SHERMAN OLGA KHORKOVA |
| 分类号 |
A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K31/713;A61P3/00;A61P3/10;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P13/12;A61P17/02;A61P19/10;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P31/12;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P43/00;C07H21/00;C07H21/04;C12N5/09;G01N25/04 |
主分类号 |
A61K31/7088 |
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