发明名称 LOW HEMOLYTIC ANTIMICROBIAL PEPTIDE, PHARMACEUTICAL COMPOSITION AND USE THEREOF
摘要 Disclosed is an antimicrobial peptide having an amino acid sequence of formula presented as (P1)M(nA1X1X2)N(P2)X, wherein P1 is selected from the group consisting of basic amino acids including Arg and Lys; A1 is selected from the group consisting of aromatic amino acids including Trp, Phe and Ala; X1 is selected from the group consisting of basic amino acids or nonpolar amino acids, including Arg, Lys, Val, Leu, Ala and Ile; X2 is selected from the group consisting of basic amino acids or nonpolar amino acids, including Arg, Lys, Val, Leu, Ala and Ile; P2 is selected from the group consisting of basic amino acids including Arg and Lys; and the numbers of M and X are respectively 0˜2; when N>2, A1 is Ala and the Ala residues are less than N−2.
申请公布号 US2011294724(A1) 申请公布日期 2011.12.01
申请号 US201113074864 申请日期 2011.03.29
申请人 CHENG JYA-WEI;HUANG KUO-CHUN;CHENG HIS-TSU;YU HUI-YUAN;RISE TECHNOLOGY CO., LTD. 发明人 CHENG JYA-WEI;HUANG KUO-CHUN;CHENG HIS-TSU;YU HUI-YUAN
分类号 A61K38/12;A61K38/08;A61K38/10;A61P31/04;A61P31/10;A61P31/12;A61P33/02;C07K7/06;C07K7/08;C07K7/64 主分类号 A61K38/12
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