| 摘要 |
<p>This invention relates to a method for the production of proteins, preferably, heterologous proteins, under the regulation of the hp4d promoter, in Yarrowia lipolytica. In particular, this invention describes a method for manipulating the growth rate of Y. lipolytica by regulating the carbon and/or nitrogen supply. A growth rate of less than 0.045 h"1 was found to be optimal for increasing Y. lipolytica biomass and increasing the amount of heterologous proteins of interest produced.</p> |
