Construction of west Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by West Nile virus
摘要
The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines.
申请公布号
AU2011250694(A1)
申请公布日期
2011.12.01
申请号
AU20110250694
申请日期
2011.11.10
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY WALTER REED ARMY INSTITUTE OF RESEARCH
发明人
PLETNEV, ALEXANDER G.;PUTNAK, JOSEPH R.;CHANOCK, ROBERT M.;MURPHY, BRIAN R.;WHITEHEAD, STEPHEN S.;BLANEY, JOSEPH E.