发明名称 |
8-HYDROXY-QUINOLINE DERIVATIVES |
摘要 |
The invention relates to compounds of the general formula (I) and their pharmaceutically acceptable salts (in which formula R1 represents a hydrogen atom, lower alkyl group, lower alkenyl group, lower cycloalkyl group, aryl group, aralkyl group or heterocyclic group, wherein the above groups are optionally substituted in ortho, meta and/or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R2 represents a hydrogen atom, lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted with one or more halogen atoms; R3 represents a lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted in ortho, meta or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R4 represents a hydrogen atom, lower alkyl group or any acidic functional group; n is 1 or 2). The compounds according to the invention can be used in the medicine mainly for the treatment of diseases associated with neurological and/or oxidative stress. |
申请公布号 |
WO2011148208(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
WO2011HU00043 |
申请日期 |
2011.05.06 |
申请人 |
"AVIDIN" KUTATO, FEJLESZTO ES KERESKEDELMI KORLATOLT FELELOSSEGU TARSASAG;PUSKAS, LASZLO;SZABO, CSABA;KANIZSAI, IVAN;GYURIS, MARIO;MADACSI, RAMONA;OZSVARI, BELA;FEHER, LILIANA;TAMAS, GABOR |
发明人 |
PUSKAS, LASZLO;SZABO, CSABA;KANIZSAI, IVAN;GYURIS, MARIO;MADACSI, RAMONA;OZSVARI, BELA;FEHER, LILIANA;TAMAS, GABOR |
分类号 |
C07D215/26;A61K31/47;A61K31/4709;A61P9/10;A61P25/28;C07D401/06;C07D401/12;C07D401/14;C07D413/12 |
主分类号 |
C07D215/26 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|