摘要 |
<p>The invention provides anti-CD 19 antibodies and methods of using the same. An isolated antibody that binds to CD 19, characterized in binding to the same CD 19 epitope to which monoclonal antibody 381 binds, which is characterized by comprising as heavy chain variable region SEQ ID NO: 1 and as light chain variable region SEQ ID NO: 5. The antibodies are useful as a therapeutic agent for treatment of autoimmune, rheumatoid arthritis, lupus, psoriasis, and bone diseases, as well as for tumor treatment.</p> |