发明名称 |
COORDINATION COMPLEXES, PHARMACEUTICAL SOLUTIONS COMPRISING COORDINATION COMPLEXES, AND METHODS OF TREATING PATIENTS |
摘要 |
A coordination complex having a physiologically acceptable pKa includes a metal and a biologically active agent. The pKa of the coordination complex is less than the pKa of the biologically active agent. A pharmaceutical solution for treating a patient includes a coordination complex and water, wherein the coordination complex is at least partially soluble in the water at physiological pH and in a therapeutically efficacious concentration. A method for treating a patient includes administering a pharmaceutical solution including a coordination complex and water to a patient in need of a biologically active agent. |
申请公布号 |
CA2799771(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
CA20112799771 |
申请日期 |
2011.05.19 |
申请人 |
SYNTHONICS, INC. |
发明人 |
PICCARIELLO, THOMAS;PRICE, JOHN D.;OBERLENDER, ROBERT A.;MULHARE, MICHAELA E.;SPENCER, MARY C.;PALMER, SCOTT B. |
分类号 |
A61K31/165;A61K31/35;A61K47/48;C07F3/02;C07F3/04;C07F9/02 |
主分类号 |
A61K31/165 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|