发明名称 |
DEGRADABLE CLOSTRIDIAL TOXINS |
摘要 |
The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain. |
申请公布号 |
US2011294742(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
US201113209969 |
申请日期 |
2011.08.15 |
申请人 |
STEWARD LANCE E.;FERNANDEZ-SALAS ESTER G.;GILMORE MARCELLA A.;FRANCIS JOSEPH;LI SHENGWEN;AOKI KEI ROGER;ALLERGAN, INC. |
发明人 |
STEWARD LANCE E.;FERNANDEZ-SALAS ESTER G.;GILMORE MARCELLA A.;FRANCIS JOSEPH;LI SHENGWEN;AOKI KEI ROGER |
分类号 |
A61K38/16;A61P1/00;A61P13/10;A61P17/00;A61P21/02;A61P25/00;A61P25/14;A61P27/02;A61P29/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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