发明名称 |
EXOGENOUS MATRIX-SUPPORTED TOPICAL APPLICATION OF STEM CELLS TO ORGAN SURFACE |
摘要 |
A process of tissue regeneration is provided that includes the administration of a stem cell topically to a surface of a tissue. The tissue being in vivo in a subject or in vitro. The tissue has a biocompatible matrix applied around the stem cell and in contact with the surface. After sufficient time, the stem cell infiltrates and regenerates the tissue. A composition is also provided that includes an injured or diseased tissue with a plurality of stem cells proximal to the tissue surface in a biocompatible. A process of increasing a level of cytokines, chemokines, growth factors, anti-apoptotic or anti-necrotic factors in a tissue is provided that includes the administration of a stem cell topically to a surface of a tissue in a biocompatible matrix. After sufficient time, the stem cell releases soluble pro-regenerative factors to increase the levels in the tissue.
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申请公布号 |
US2011296542(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
US201113149186 |
申请日期 |
2011.05.31 |
申请人 |
WANG KEVIN KA-WANG;KUEN LAM PING;FAI NG CHI;SIMON NG SIU MAN;TONY MAK WING CHUNG;SANG POON WAI;PAUL LAI BO SAN |
发明人 |
WANG KEVIN KA-WANG;KUEN LAM PING;FAI NG CHI;SIMON NG SIU MAN;TONY MAK WING CHUNG;SANG POON WAI;PAUL LAI BO SAN |
分类号 |
A01K67/027;A61K35/12;A61K35/14;A61K35/44;A61P43/00 |
主分类号 |
A01K67/027 |
代理机构 |
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