| 发明名称 |
NOVEL POLYMORPHS OF LOPINAVIR |
| 摘要 |
The present invention provides a novel cyclohexane solvate form of lopinavir, and a process for its preparation thereof. The present invention also provides a novel desolvated crystalline form of lopinavir, process for its preparation and to pharmaceutical composition containing it. Thus, for example, lopinavir cyclohexane solvate was heated at 100° C. for 10 hours to give lopinavir desolvated crystalline form H1. |
| 申请公布号 |
US2011294839(A1) |
申请公布日期 |
2011.12.01 |
| 申请号 |
US200913121505 |
申请日期 |
2009.02.06 |
| 申请人 |
PARTHASARADHI REDDY BANDI;RATHNAKAR REDDY KURA;RAJI REDDY RAPOLU;MURALIDHARA REDDY DASARI;SUBASH CHANDER REDDY KESIREDDY;HETERO RESEARCH FOUNDATION |
发明人 |
PARTHASARADHI REDDY BANDI;RATHNAKAR REDDY KURA;RAJI REDDY RAPOLU;MURALIDHARA REDDY DASARI;SUBASH CHANDER REDDY KESIREDDY |
| 分类号 |
A61K31/513;A61P31/18;C07D239/10 |
主分类号 |
A61K31/513 |
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