发明名称 |
COLORIMETRIC BIOSENSOR WITH ALLOSTERIC DNAZYME ACTIVATION AND ROLLING CIRCLE SIGNAL AMPLIFICATION |
摘要 |
The present disclosure includes a method of determining the presence of a target in a sample comprising an allosteric DNAzyme; rolling circle amplification dependent on the activity of the allosteric DNAzyme in the presence of target and a detection system. The methods further comprise quantifying the amount of target in the sample by comparing the detection with a control. Also included herein are kits for practicing the methods described herein and methods of designing biosensor systems. |
申请公布号 |
US2011294125(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
US200913141007 |
申请日期 |
2009.12.18 |
申请人 |
LI YINGFU;ALI MONSUR;MCMASTER UNIVERSITY |
发明人 |
LI YINGFU;ALI MONSUR |
分类号 |
C12Q1/68;B82Y15/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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