发明名称 |
METHOD FOR MODULATING MUSCLE DIFFERENTIATION OR REGENERATION |
摘要 |
Present invention relates to method for promoting or inhibiting muscle differentiation or regeneration using an enhancer or an inhibitor capable of modulating the binding of TAZ polypeptide with MyoD polypeptide; method for screening a substance capable of up- or down-regulating muscle differentiation or regeneration by use of interaction between TAZ polypeptide and MyoD polypeptide; an isolated peptide consisting of an amino acid sequence of SEQ ID NO. 2 which binds to and activates the MyoD polypeptide; a polynucleotide encoding the isolated peptide; and a pharmaceutical composition comprising the isolated peptide or the polynucleotide. |
申请公布号 |
US2011293599(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
US201113086593 |
申请日期 |
2011.04.14 |
申请人 |
HWANG EUN SOOK;EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION |
发明人 |
HWANG EUN SOOK |
分类号 |
A61K39/395;A61K31/7088;A61K38/02;A61K38/17;A61P9/00;A61P9/10;A61P21/00;A61P25/00;C07H21/00;C07K14/47;C12N5/077;C12N15/63;G01N33/68 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|