发明名称 |
PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION |
摘要 |
<p>A pharmaceutical composition containing one or more antifungal agents selected from an arylamidine derivative represented by the general formula:
(wherein R 1 represents an amidino group that may be substituted with a hydroxyl group that may be protected with an acyl group, an amidino group that may be substituted with an alkoxy group that may be substituted, or an amidino group that may be substituted with an aralkyloxy group that may be substituted; R 2 and R 3 identically or differently represent a hydrogen atom or a halogen atom) or a salt thereof, an azole antifungal agent, a polyene antifungal agent, a candin antifungal agent and a fluoropyrimidine antifungal agent has a strong antifungal activity and is useful for the treatment of fungal infection. A method for using them in combination is useful as an excellent therapeutic method for fungal infection. A pharmaceutical composition containing the arylamidine derivative represented by the above general formula or a salt thereof and an immunosuppressant has a strong antifungal activity and is useful for the treatment of fungal infection and a skin disease such as atopic dermatitis. A method for using them in combination is useful as an excellent therapeutic method for fungal infection and a skin disease such as atopic dermatitis.</p> |
申请公布号 |
SI1867332(T1) |
申请公布日期 |
2011.11.30 |
申请号 |
SI20060031142T |
申请日期 |
2006.04.05 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
NOMURA NOBUHIKO;NISHIKAWA HIROSHI;FUJINO NORITOMO |
分类号 |
A61K31/445;A61K31/4196;A61K31/7042 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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