发明名称 |
GLYCAN ARRAYS ON PTFE-LIKE ALUMINUM COATED GLASS SLIDES AND RELATED METHODS |
摘要 |
Aluminum coated glass slides provide a novel glycan array platform. Specifically, aluminum coated glass slides increase sensitivity of fluorescent based assay methods. Additionally, aluminum coated glass slides allows for mass spectroscopic analysis of carbohydrates and provide a platform for examining activity of cellulases. The unique properties of ACG slides include: 1) the metal oxide layer on the surface can be activated for grafting organic compounds such as modified oligosaccharides; 2) the surface remains electrically conductive, and the grafted oligosaccharides can be simultaneously characterized by mass spectrometry and carbohydrate-binding assay; and 3) the slides are more sensitive than transparent glass slides in binding analysis. |
申请公布号 |
EP2318832(A4) |
申请公布日期 |
2011.11.30 |
申请号 |
EP20090798721 |
申请日期 |
2009.07.15 |
申请人 |
ACADEMIA SINICA |
发明人 |
WONG, CHI-HUEY;WU,CHUNG-YI;TSENG, SUSAN Y. |
分类号 |
G01N33/50;G01N33/66;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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地址 |
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