发明名称 COMPOSITIONS AND METHODS FOR CRYSTALLIZING ANTIBODIES
摘要 The present invention relates to a batch crystallization method for crystallizing anti-human TNFalpha (hTNFalpha) antibody and antibody fragments which allows the production of said antibody on an industrial scale; a method of controlling the size of antibody crystals, for example, crystals of anti-hTNFalpha antibody fragments, compositions containing said crystals as well as methods of use of said crystals and compositions.
申请公布号 EP2185201(A4) 申请公布日期 2011.11.30
申请号 EP20080795162 申请日期 2008.08.08
申请人 ABBOTT LABORATORIES 发明人 FRAUNHOFER, WOLFGANG;BORHANI, DAVID W.;WINTER, GERHARD;GOTTSCHALK, STEFAN
分类号 C12N15/10;A61K39/395;C07K16/24 主分类号 C12N15/10
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