发明名称 |
COMPOSITIONS AND METHODS FOR CRYSTALLIZING ANTIBODIES |
摘要 |
The present invention relates to a batch crystallization method for crystallizing anti-human TNFalpha (hTNFalpha) antibody and antibody fragments which allows the production of said antibody on an industrial scale; a method of controlling the size of antibody crystals, for example, crystals of anti-hTNFalpha antibody fragments, compositions containing said crystals as well as methods of use of said crystals and compositions. |
申请公布号 |
EP2185201(A4) |
申请公布日期 |
2011.11.30 |
申请号 |
EP20080795162 |
申请日期 |
2008.08.08 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
FRAUNHOFER, WOLFGANG;BORHANI, DAVID W.;WINTER, GERHARD;GOTTSCHALK, STEFAN |
分类号 |
C12N15/10;A61K39/395;C07K16/24 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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