The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.
申请公布号
EP2389352(A2)
申请公布日期
2011.11.30
申请号
EP20100734002
申请日期
2010.01.26
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;ARGINETIX, INC.