发明名称 |
VIRUS GROWING IN HYPOXIC CELL OR VIRUS VECTOR EXPRESSING GENE THEREIN |
摘要 |
The present invention provides a virus or a viral vector capable of expressing a gene specifically in a cell having replication ability in a hypoxic state such as a cancer stem cell and injuring the cell, and a pharmaceutical composition comprising the same. Specifically, the present invention provides a virus or a viral vector which comprises a gene encoding a fusion protein of an ODD and a protein essentially required for viral proliferation, and a pharmaceutical composition comprising the same. |
申请公布号 |
EP2239325(A4) |
申请公布日期 |
2011.11.30 |
申请号 |
EP20090702346 |
申请日期 |
2009.01.13 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY;TAKAHASHI, KATSUHITO;YAMAMURA, HISAKO |
发明人 |
TAKAHASHI, KATSUHITO;YAMAMURA, HISAKO;INOUE, MASAHIRO |
分类号 |
C12N15/09;A61K35/76;A61P9/10;A61P11/00;A61P25/00;A61P35/00;C07K14/03;C07K14/035;C07K14/47;C07K19/00;C12N7/00;C12N15/869 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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