| 发明名称 |
SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS |
| 摘要 |
The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of the peptide boronic acid proteasome inhibitor bortezomib. |
| 申请公布号 |
PT1756121(E) |
申请公布日期 |
2011.11.30 |
| 申请号 |
PT20050742865T |
申请日期 |
2005.03.24 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
I. FRASER PICKERSGILL;JOHN BISHOP;CHRISTOPH KOELLNER;JEAN-MARC GOMEZ;ACHIM GEISER;ROBERT HETT;VINCE AMMOSCATO;STEPHEN MUNK;YOUNG BOEHRINGER LO;FANG-TING CHUI;V. R. KULKARNI |
| 分类号 |
C07F5/02;C07F5/04 |
主分类号 |
C07F5/02 |
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