| 发明名称 |
Methods of using human tissue factor-producing knock-in mice |
| 摘要 |
A non-human animal that produces human tissue factor (TF) without substantially producing non-human animal tissue factor, said animal having a genome in which cDNA encoding human TF has been inserted upstream of the translation initiation codon for the non-human animal genomic TF gene. |
| 申请公布号 |
US8067665(B2) |
申请公布日期 |
2011.11.29 |
| 申请号 |
US20090461453 |
申请日期 |
2009.08.12 |
| 申请人 |
HABU KIYOSHI;JISHAGE KOU-ICHI;ADACHI HIDEKI;YABUTA NAOHIRO;CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
HABU KIYOSHI;JISHAGE KOU-ICHI;ADACHI HIDEKI;YABUTA NAOHIRO |
| 分类号 |
C12P21/00;A01K67/027;C12N15/85 |
主分类号 |
C12P21/00 |
| 代理机构 |
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代理人 |
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