METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES.

摘要

The invention relates to a method for producing oxindoles and ortho-substituted anilines and the use thereof as intermediate products for syntheses. Method for producing compounds of the formula (4): wherein a mixture of an aniline (compound of the formula Q) is converted with a thioether (compound of the formula W) in the presence of a chlorinating agent and an organic solvent at a reaction temperature in the range from –60° to –10°C. In a subsequent method, said compound is further converted in the presence of an acid catalyst to the indole of the formula (7) or the oxindole of the formula (8).