| 发明名称 |
Histone deacetylase inhibitors and methods of use thereof |
| 摘要 |
One aspect of the invention relates to HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided. The invention also provides methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention. |
| 申请公布号 |
US8067600(B2) |
申请公布日期 |
2011.11.29 |
| 申请号 |
US20080339492 |
申请日期 |
2008.12.19 |
| 申请人 |
KOZIKOWSKI ALAN P.;CHEN BIN;GEORGETOWN UNIVERSITY |
发明人 |
KOZIKOWSKI ALAN P.;CHEN BIN |
| 分类号 |
C07D217/12;A01N37/10;A01N43/40;A01N43/42;A61K;A61K31/19;A61K31/47;C07C259/04;C07C259/06;C07C271/02;C07C275/24;C07C275/26;C07C275/40;C07C323/44;C07C323/60;C07D215/14;C07D215/48;C07D215/54 |
主分类号 |
C07D217/12 |
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