发明名称 |
NOVEL POLYSIALIC ACID-DEGRADING ENDO-POLYSIALIDASE, ITS PREPARATION FROM PSEUDOMONAS FLUORESCENS JK-0412 AND USES THEREOF |
摘要 |
PURPOSE: A method for producing sialidase using Pseudomonas fluorescens JK-0412 is provided to ensure anti-viral, anticancer, and diabetic activities. CONSTITUTION: A sialidase contains N-terminal amino acid sequence of sequence number 4. The peptide specifically hydrolyzes alpha-2,8-linked polysialic acid. The peptide is derived from Pseudomonas fluoescens JK-0412(deposit number KCTC 11623BP). The peptide is prepared by culturing the Pseudomonas fluoescens JK-0412 under the presence of chitin as a carbon source. The peptide is contained in a supernatant of culture liquid of Pseudomonas fluoescens JK-0412. The Pseudomonas fluoescens JK-0412 is cultured at 25-50 °C and pH 4-10.
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申请公布号 |
KR20110128263(A) |
申请公布日期 |
2011.11.29 |
申请号 |
KR20110119031 |
申请日期 |
2011.11.15 |
申请人 |
CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION |
发明人 |
PARK, YONG IL;PARK, JAE KWEON;JIN CHENG MIN;CHOI, DOO JIN |
分类号 |
C12N9/14;C07K14/21;C12N15/31 |
主分类号 |
C12N9/14 |
代理机构 |
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