| 摘要 |
The hexuronic acid derivative represented by the following formula 1 or a salt thereof is used as an active ingredient of a heparin/heparan sulfate sulfotransferase inhibitor. [Chemical formula 1] (see formula 1) In the formula, each of R1, R2, and R3 independently represent(s) SO3- or H which may have a substituent, provided that at least one thereof represents SO3-; X represents OR4, SR4, N(R4)2, or C(R4)3, R4 independently represents H, alkyl, alkenyl, alkynyl, acyl, aryl, or aralkyl group; one of R5 and R6 represents COOH while the other represents H; and the wavy line represents .alpha.-glycosidic bond or .beta.-glycosidic bond.
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