发明名称 siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)
摘要 Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to STK12.
申请公布号 US8067576(B2) 申请公布日期 2011.11.29
申请号 US20100657448 申请日期 2010.01.21
申请人 KHVOROVA ANASTASIA;REYNOLDS ANGELA;LEAKE DEVIN;MARSHALL WILLIAM;READ STEVEN;SCARINGE STEPHEN;DHARMACON, INC. 发明人 KHVOROVA ANASTASIA;REYNOLDS ANGELA;LEAKE DEVIN;MARSHALL WILLIAM;READ STEVEN;SCARINGE STEPHEN
分类号 A61K31/70;C07H21/04;C12N15/11;C12N15/113 主分类号 A61K31/70
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