发明名称 |
PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLINES |
摘要 |
The present invention concerns new processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines which are useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF.alpha.. The invention provides processes for the commercial production of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines including, but not limited to, the therapeutically active 3-(4-amino-1-oxoisoindolin-2-yl) piperidine-2,6-dione.
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申请公布号 |
CA2579291(C) |
申请公布日期 |
2011.11.29 |
申请号 |
CA20052579291 |
申请日期 |
2005.08.31 |
申请人 |
CELGENE CORPORATION |
发明人 |
MULLER, GEORGE W.;CHEN, ROGER;SAINDANE, MANOHAR TUKARAM;GE, CHUANSHENG |
分类号 |
C07D401/04;C07D209/46 |
主分类号 |
C07D401/04 |
代理机构 |
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