发明名称 |
Method for treatment of constipation-predominant irritable bowel syndrome |
摘要 |
The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome. |
申请公布号 |
US8067041(B2) |
申请公布日期 |
2011.11.29 |
申请号 |
US20090476590 |
申请日期 |
2009.06.02 |
申请人 |
QUART BARRY D.;ROSENBAUM DAVID P.;NAPO PHARMACEUATICALS, INC. |
发明人 |
QUART BARRY D.;ROSENBAUM DAVID P. |
分类号 |
A61K36/00;A61K31/353;A61K36/47 |
主分类号 |
A61K36/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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