发明名称 DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF
摘要 <p>The inventions relates to the compounds of formula (I) where: R is a hydrogen atom or a group selected from the (C1d- C6)alkyl and (C3-C7)-cycloalkyl groups, optionally substituted by one or more groups independently selected from a fluorine atom, the (C3-C7)-cycloalkyl, (C2-C4)alkenyl, phenyl, (C1-C6)alkoxy, and hydroxy groups; the phenyl group being optionally substituted by one or more (C1-C6)alkoxy groups; R1 is a phenyl group optionally substituted by one or more substituants independently selected from halogen atoms, the (C1-C6)alkyl, (C1-C6)alkoxy, halo-(C1C6)alkyl, hydroxy, halo-(C1-C6)alkoxy, (C1-C6)alkyl-thio, and (C1-C6)alkyl-SO2 groups; R2 is one or more substituants selected from hydrogen atoms, halogen atoms, the halo-(C1-C6)alkyl, (C1-C6)alkyl, (C3-C7)cycloalkyl, (C3-C7)-cycloalkyl-(C1-C3)alkyl, (C1C6)alkoxy, (C1C6)alkyl-thio, and (C1-C6)alkyl-SO2 groups; in the form of a base or an addition salt to an acid. The invention further relates to the use thereof in therapy and to a method for synthesizing same.</p>
申请公布号 SG175222(A1) 申请公布日期 2011.11.28
申请号 SG20110075017 申请日期 2010.04.13
申请人 SANOFI 发明人 DARGAZANLI, GIHAD;ESTENNE-BOUHTOU, GENEVIEVE
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