发明名称 |
A conjugate comprsing the amino acid sequence LPWKPLG for targeting compounds to brain cells, neuronal cells or tumour cells of neuronal or neuroectodermal origin |
摘要 |
Disclosed is a conjugate of a peptide or peptidomimetic comprising a sequence or consisting of a sequence of LPWKPLG linked to a moiety selected from a biological active moiety and diagnostic moiety. Also disclosed is the use of said conjugate for the preparation of a medicament for targeting a biological active moiety or a diagnostic moiety across the blood brain barrier to brain cells, to neuronal cells or to tumour cells of neuronal or neuroectodermal origin.
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申请公布号 |
NZ582522(A) |
申请公布日期 |
2011.11.25 |
申请号 |
NZ20080582522 |
申请日期 |
2008.07.11 |
申请人 |
PROSENSA TECHNOLOGIES B.V. |
发明人 |
VAN KUIK-ROMEIJN, PETRA;PLATENBURG, GERARD JOHANNES |
分类号 |
A61K47/48;A61P21/00;A61P25/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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