发明名称 PYRIDIN-4-YL DERIVATIVES AS IMMUNOMODULATING AGENTS
摘要 Disclosed is a pyridine-4-yl derivative compound of the formula (I), wherein A, R1, R2, R3, R4, R5, and R6 are as described in the description. Also disclosed is the use of the compound for the preparation of a pharmaceutical composition for the prevention or treatment of diseases or disorders selected from the group consisting of rejection of transplanted organs; graft-versus-host diseases brought about by stem cell transplantation; autoimmune syndromes; atopic diseases; asthma; type I diabetes; post-infectious autoimmune diseases; solid cancers and tumour metastasis.
申请公布号 NZ576060(A) 申请公布日期 2011.11.25
申请号 NZ20070576060 申请日期 2007.09.06
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 LEHMANN, DAVID;MATHYS, BORIS;BOLLI, MARTIN;MUELLER, CLAUS;NAYLER, OLIVER;STEINER, BEAT;VELKER, JORG
分类号 C07D417/04;A61K31/4439;A61P9/00;A61P19/00;A61P35/00;A61P37/00;C07D413/04 主分类号 C07D417/04
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